Memphis Depay starred with two goals and two assists as fourth-placed Lyon won at bottom side Guingamp 4-2 in Ligue 1 on Saturday.
Thierry Henry is still waiting for his first win as Monaco head coach after a 1-0 loss at Reims.
Paris Saint-Germain matched Tottenham's long-standing European record by beating Marseille 2-0 to record an 11th straight league win.
Patrick Vieira's Nice slumped to a fourth defeat in five home league games after losing 1-0 against Marseille on Sunday.
Neymar scored twice as Paris St-Germain continued their perfect start to the Ligue 1 season with a 3-0 victory at Nice.
Monaco were beaten for the third time in seven games as Angers left the principality with a shock 1-0 win.
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