Barcelona moved three points clear at the top of La Liga following an impressive 4-0 win at derby rivals Espanyol.
Denis Suarez struck twice for Copa del Rey holders Barcelona as they thrashed Cultural Leonesa 4-1 on Wednesday to progress to the last 16 5-1 on aggregate.
Barcelona returned to the top of La Liga with a comfortable 2-0 victory against
Villarreal at the Nou Camp.
Alaves missed the chance to jump to the top of the La Liga table, falling to a surprise 1-0 loss at struggling Leganes.
Sevilla and Alaves moved level on points with Atletico Madrid - and one point behind leaders Barcelona - in La Liga after fighting back for victories.
Alaves missed the chance to go second in La Liga after conceding an injury-time goal in a fiery 2-1 defeat to Basque rivals Eibar.
Surprise packages Alaves are second in La Liga after beating struggling Villarreal 2-1 on Sunday, while Sevilla also won.
Real Madrid's miserable run continued as they slid to a last-gasp 1-0 La Liga defeat at Alaves on Saturday, marking their longest run without scoring in over 33 years.
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