La Liga leaders Barcelona were held to a goalless draw by basement club Huesca on Saturday.
Getafe moved a step closer to earning Champions League football for the first
time in their history after beating Athletic Bilbao 1-0 on Sunday.
Zinedine Zidane suffered his first defeat since retaking the reins at Real Madrid as Valencia ran out 2-1 winners at the Mestalla.
Lionel Messi scored twice as Barcelona won for the sixth time in a row against rivals Espanyol.
Zinedine Zidane's second stint at Real Madrid began with victory as Isco and Gareth Bale both scored in the 2-0 La Liga win over Celta Vigo.
Scroll back through updates as Zinedine Zidane wins his first game back in charge of Real Madrid thanks to goals from Isco and Gareth Bale.
Wissam Ben Yedder bagged a 13-minute hat-trick in the second half as Sevilla cruised to a 5-2 triumph over Real Sociedad in La Liga.
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